6otd: Difference between revisions

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<StructureSection load='6otd' size='340' side='right'caption='[[6otd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='6otd' size='340' side='right'caption='[[6otd]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6otd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anadf Anadf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OTD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OTD FirstGlance]. <br>
<table><tr><td colspan='2'>[[6otd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaeromyxobacter_sp._Fw109-5 Anaeromyxobacter sp. Fw109-5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OTD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ohe|5ohe]], [[5ohf|5ohf]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gchK, Anae109_2438 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=404589 ANADF])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6otd OCA], [https://pdbe.org/6otd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6otd RCSB], [https://www.ebi.ac.uk/pdbsum/6otd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6otd ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6otd OCA], [http://pdbe.org/6otd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6otd RCSB], [http://www.ebi.ac.uk/pdbsum/6otd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6otd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GCHK_ANADF GCHK_ANADF]] Member of the two-component regulatory system GcHK/Anae109_2439. Autophosphorylates in response to oxygen availability, and then transfers the phosphate group to a conserved Asp residue in the receiver domains of the cognate response regulator Anae109_2439, resulting in its activation.<ref>PMID:21852234</ref>
[https://www.uniprot.org/uniprot/GCHK_ANADF GCHK_ANADF] Member of the two-component regulatory system GcHK/Anae109_2439. Autophosphorylates in response to oxygen availability, and then transfers the phosphate group to a conserved Asp residue in the receiver domains of the cognate response regulator Anae109_2439, resulting in its activation.<ref>PMID:21852234</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anadf]]
[[Category: Anaeromyxobacter sp. Fw109-5]]
[[Category: Histidine kinase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dohnalek, J]]
[[Category: Dohnalek J]]
[[Category: Kolenko, P]]
[[Category: Kolenko P]]
[[Category: Lengalova, A]]
[[Category: Lengalova A]]
[[Category: Martinkova, M]]
[[Category: Martinkova M]]
[[Category: Skalova, T]]
[[Category: Skalova T]]
[[Category: Stranava, M]]
[[Category: Stranava M]]
[[Category: Globin domain]]
[[Category: Globin sensor domain]]
[[Category: Heme]]
[[Category: Imidazole]]
[[Category: Oxygen sensor]]
[[Category: Sensor protein]]
[[Category: Transferase]]