6pi9: Difference between revisions

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<StructureSection load='6pi9' size='340' side='right'caption='[[6pi9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='6pi9' size='340' side='right'caption='[[6pi9]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6pi9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PI9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PI9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6pi9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PI9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rmtF, pN11x00042NDM_104 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/16S_rRNA_(guanine(1405)-N(7))-methyltransferase 16S rRNA (guanine(1405)-N(7))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.179 2.1.1.179] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pi9 OCA], [https://pdbe.org/6pi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pi9 RCSB], [https://www.ebi.ac.uk/pdbsum/6pi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pi9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6pi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pi9 OCA], [http://pdbe.org/6pi9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6pi9 RCSB], [http://www.ebi.ac.uk/pdbsum/6pi9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6pi9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/I1YZZ5_KLEPN I1YZZ5_KLEPN]] Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides.[PIRNR:PIRNR015852]  
[https://www.uniprot.org/uniprot/I1YZZ5_KLEPN I1YZZ5_KLEPN] Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides.[PIRNR:PIRNR015852]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Di Leo R]]
[[Category: Evdokimova, E]]
[[Category: Evdokimova E]]
[[Category: Joachimiak, A]]
[[Category: Joachimiak A]]
[[Category: Kim, Y]]
[[Category: Kim Y]]
[[Category: Leo, R Di]]
[[Category: Satchell KJF]]
[[Category: Satchell, K J.F]]
[[Category: Savchenko A]]
[[Category: Savchenko, A]]
[[Category: Semper C]]
[[Category: Semper, C]]
[[Category: Stogios PJ]]
[[Category: Stogios, P J]]
[[Category: 16s rrna]]
[[Category: Antibiotic resistance]]
[[Category: Csgid]]
[[Category: Methyltransferase]]
[[Category: Methyltransferase domain]]
[[Category: Plasmid]]
[[Category: Transferase]]

Latest revision as of 07:30, 11 October 2023

Crystal structure of 16S rRNA methyltransferase RmtF in complex with S-Adenosyl-L-homocysteine

6pi9, resolution 1.85Å

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