6pon: Difference between revisions
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<StructureSection load='6pon' size='340' side='right'caption='[[6pon]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='6pon' size='340' side='right'caption='[[6pon]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6pon]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6pon]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PON FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.395Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pon OCA], [https://pdbe.org/6pon PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pon RCSB], [https://www.ebi.ac.uk/pdbsum/6pon PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pon ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RQCH_STRR6 RQCH_STRR6] Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.[HAMAP-Rule:MF_00844] Recombinant protein binds to immobilized human fibronectin; binding is saturable and competed by heparin. Recombinant protein inhibits binding of whole cells to fibronectin.<ref>PMID:11580843</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Streptococcus pneumoniae]] | ||
[[Category: | [[Category: Manne K]] | ||
[[Category: | [[Category: Narayana SVL]] | ||