6u2u: Difference between revisions

<table><tr><td colspan='2'>[[6u2u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6U2U FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6u2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u2u OCA], [https://pdbe.org/6u2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6u2u RCSB], [https://www.ebi.ac.uk/pdbsum/6u2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6u2u ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ID1_MOUSE ID1_MOUSE] Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.<ref>PMID:16556596</ref> <ref>PMID:19217292</ref>  

[[Category: Mus musculus]]

[[Category: Benezra R]]

[[Category: Gall A-L]]

[[Category: Goldgur Y]]

[[Category: Pavletich NP]]