6vqn: Difference between revisions

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<StructureSection load='6vqn' size='340' side='right'caption='[[6vqn]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
<StructureSection load='6vqn' size='340' side='right'caption='[[6vqn]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6vqn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VQN FirstGlance]. <br>
<table><tr><td colspan='2'>[[6vqn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VQN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R81:N,N-(2,2-dimethyl[1,1-biphenyl]-3,3-diyl)bis(5-{[(2-hydroxyethyl)amino]methyl}pyridine-2-carboxamide)'>R81</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.49&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=R81:N,N-(2,2-dimethyl[1,1-biphenyl]-3,3-diyl)bis(5-{[(2-hydroxyethyl)amino]methyl}pyridine-2-carboxamide)'>R81</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vqn OCA], [https://pdbe.org/6vqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vqn RCSB], [https://www.ebi.ac.uk/pdbsum/6vqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vqn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vqn OCA], [https://pdbe.org/6vqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vqn RCSB], [https://www.ebi.ac.uk/pdbsum/6vqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vqn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN]] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>
[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lakshminarasimhan, D]]
[[Category: Lakshminarasimhan D]]
[[Category: Leo, C]]
[[Category: Leo C]]
[[Category: Suto, R K]]
[[Category: Suto RK]]
[[Category: White, A]]
[[Category: White A]]
[[Category: Cell cycle]]
[[Category: Complex]]
Retrieved from "https://proteopedia.org/6vqn"