6vus: Difference between revisions
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<StructureSection load='6vus' size='340' side='right'caption='[[6vus]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='6vus' size='340' side='right'caption='[[6vus]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6vus]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[6vus]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VUS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RNV:2-[(4-amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-[2-(diethylamino)ethyl]acetamide'>RNV</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RNV:2-[(4-amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-[2-(diethylamino)ethyl]acetamide'>RNV</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vus OCA], [https://pdbe.org/6vus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vus RCSB], [https://www.ebi.ac.uk/pdbsum/6vus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vus ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vus OCA], [https://pdbe.org/6vus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vus RCSB], [https://www.ebi.ac.uk/pdbsum/6vus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vus ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Garneau-Tsodikova | [[Category: Garneau-Tsodikova S]] | ||
[[Category: Hou | [[Category: Hou C]] | ||
[[Category: Ngo | [[Category: Ngo HX]] | ||
[[Category: Punetha | [[Category: Punetha A]] | ||
[[Category: Tsodikov | [[Category: Tsodikov OV]] | ||
Latest revision as of 08:20, 11 October 2023
Crystal structure of Eis from Mycobacterium tuberculosis in complex with inhibitor SGT379
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