3b0v: Difference between revisions

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<StructureSection load='3b0v' size='340' side='right'caption='[[3b0v]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
<StructureSection load='3b0v' size='340' side='right'caption='[[3b0v]], [[Resolution|resolution]] 3.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3b0v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ ] and [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B0V FirstGlance]. <br>
<table><tr><td colspan='2'>[[3b0v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B0V FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.51&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3b0p|3b0p]], [[3b0u|3b0u]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTHA0016 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b0v OCA], [https://pdbe.org/3b0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b0v RCSB], [https://www.ebi.ac.uk/pdbsum/3b0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b0v ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b0v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b0v OCA], [https://pdbe.org/3b0v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b0v RCSB], [https://www.ebi.ac.uk/pdbsum/3b0v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b0v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/Q5SMC7_THET8 Q5SMC7_THET8]] Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity).[PIRNR:PIRNR006621]  
[https://www.uniprot.org/uniprot/DUSAL_THET8 DUSAL_THET8] Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.[HAMAP-Rule:MF_02041]<ref>PMID:22123979</ref> <ref>PMID:25902496</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Thet8]]
[[Category: Thermus thermophilus HB8]]
[[Category: Nakamura, A]]
[[Category: Nakamura A]]
[[Category: Tanaka, I]]
[[Category: Tanaka I]]
[[Category: Tanaka, Y]]
[[Category: Tanaka Y]]
[[Category: Yamashita, K]]
[[Category: Yamashita K]]
[[Category: Yao, M]]
[[Category: Yao M]]
[[Category: Yu, F]]
[[Category: Yu F]]
[[Category: Oxidoreductase-rna complex]]
[[Category: Tim barrel]]