7ry7: Difference between revisions

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<StructureSection load='7ry7' size='340' side='right'caption='[[7ry7]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='7ry7' size='340' side='right'caption='[[7ry7]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7ry7]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6ors 6ors]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RY7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[7ry7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6ors 6ors]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RY7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ry7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ry7 OCA], [https://pdbe.org/7ry7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ry7 RCSB], [https://www.ebi.ac.uk/pdbsum/7ry7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ry7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ry7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ry7 OCA], [https://pdbe.org/7ry7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ry7 RCSB], [https://www.ebi.ac.uk/pdbsum/7ry7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ry7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLM10_PLAF7 PLM10_PLAF7] During the asexual blood stage, processes key proteins essential for merozoite egress and invasion of host erythrocytes (PubMed:29074775, PubMed:32109369). Cleaves and activates proteases SUB1 and SUB2 (PubMed:29074775, PubMed:32109369). May process members of the EBL and Rh protein families (PubMed:32109369). Also cleaves apical membrane protein AMA1 (PubMed:29074775). During the mosquito vector stage and probably in ookinetes, cleaves CelTOS (PubMed:29074775).<ref>PMID:29074775</ref> <ref>PMID:32109369</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pepsin A]]
[[Category: Plasmodium falciparum 3D7]]
[[Category: Structural genomic]]
[[Category: Hydrolase]]
[[Category: Plasmepsin x]]
[[Category: Plasmodium falciparum]]
[[Category: Pm10]]
[[Category: Pmx]]
[[Category: Ssgcid]]