5ljx: Difference between revisions

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<StructureSection load='5ljx' size='340' side='right'caption='[[5ljx]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
<StructureSection load='5ljx' size='340' side='right'caption='[[5ljx]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ljx]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LJX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LJX FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ljx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hantaan_orthohantavirus Hantaan orthohantavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LJX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LJX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ljx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ljx OCA], [http://pdbe.org/5ljx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ljx RCSB], [http://www.ebi.ac.uk/pdbsum/5ljx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ljx ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUL:BETA-L-FUCOSE'>FUL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ljx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ljx OCA], [https://pdbe.org/5ljx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ljx RCSB], [https://www.ebi.ac.uk/pdbsum/5ljx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ljx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GP_HANTV GP_HANTV]] Glycoprotein N and Glycoprotein C interact with each. other and are present at the surface of the virion. They are able to attach the virion to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Also promote fusion of viral membrane with host endosomal membrane after endocytosis of the virion. Glycoprotein N contains an ITAM motif which is likely to dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis (By similarity).<ref>PMID:11886265</ref>
[https://www.uniprot.org/uniprot/GP_HANTV GP_HANTV] Glycoprotein N and Glycoprotein C interact with each. other and are present at the surface of the virion. They are able to attach the virion to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Also promote fusion of viral membrane with host endosomal membrane after endocytosis of the virion. Glycoprotein N contains an ITAM motif which is likely to dysregulate normal immune and endothelial cell responses and contribute to virus pathogenesis (By similarity).<ref>PMID:11886265</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hantaan orthohantavirus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Guardado-Calvo, P]]
[[Category: Guardado-Calvo P]]
[[Category: Rey, F A]]
[[Category: Rey FA]]
[[Category: Glycoprotein]]
[[Category: Hantavirus]]
[[Category: Viral fusion]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/5ljx"