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==Binding domain of Botulinum Neurotoxin DC in complex with SialylT==
==Binding domain of Botulinum Neurotoxin DC in complex with SialylT==
<StructureSection load='5lr0' size='340' side='right' caption='[[5lr0]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='5lr0' size='340' side='right'caption='[[5lr0]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5lr0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_botulinus"_van_ermengem_1896 "bacillus botulinus" van ermengem 1896]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LR0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LR0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5lr0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LR0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4isr|4isr]], [[4isq|4isq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bont, boNT D, C, DC, NT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1491 "Bacillus botulinus" van Ermengem 1896])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lr0 OCA], [https://pdbe.org/5lr0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lr0 RCSB], [https://www.ebi.ac.uk/pdbsum/5lr0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lr0 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Bontoxilysin Bontoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.69 3.4.24.69] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lr0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lr0 OCA], [http://pdbe.org/5lr0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lr0 RCSB], [http://www.ebi.ac.uk/pdbsum/5lr0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lr0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5JGM8_CLOBO A5JGM8_CLOBO]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5lr0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5lr0" style="background-color:#fffaf0;"></div>
==See Also==
*[[Botulinum neurotoxin 3D structures|Botulinum neurotoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus botulinus van ermengem 1896]]
[[Category: Clostridium botulinum]]
[[Category: Bontoxilysin]]
[[Category: Large Structures]]
[[Category: Berntsson, R P.A]]
[[Category: Berntsson RP-A]]
[[Category: Stenmark, P]]
[[Category: Stenmark P]]
[[Category: Botulnimun neurotoxin]]
[[Category: Carbohydrate binding]]
[[Category: Hydrolase]]

Latest revision as of 18:41, 18 October 2023

Binding domain of Botulinum Neurotoxin DC in complex with SialylT

5lr0, resolution 2.59Å

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