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| | | #REDIRECT [[8p7r]] This PDB entry is obsolete and replaced by 8p7r |
| ==Phosphotriesterase PTE_C23_4==
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| <StructureSection load='6fvp' size='340' side='right'caption='[[6fvp]], [[Resolution|resolution]] 1.85Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[6fvp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FVP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FVP FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E8N:1-ethyl-1-methyl-cyclohexane'>E8N</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GB:METHYLPHOSPHONIC+ACID+ESTER+GROUP'>GB</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6fee|6fee]], [[6fef|6fef]], [[6fei|6fei]], [[6fev|6fev]], [[6ffw|6ffw]], [[6for|6for]], [[6frz|6frz]], [[6fqe|6fqe]], [[6fs3|6fs3]], [[6fu0|6fu0]], [[6fu6|6fu6]], [[6fvk|6fvk]]</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fvp OCA], [http://pdbe.org/6fvp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fvp RCSB], [http://www.ebi.ac.uk/pdbsum/6fvp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fvp ProSAT]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/OPD_BREDI OPD_BREDI]] Has an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates. All of the phosphate triesters found to be substrates are synthetic compounds. The identity of any naturally occurring substrate for the enzyme is unknown. Has no detectable activity with phosphate monoesters or diesters and no activity as an esterase or protease. It catalyzes the hydrolysis of the insecticide paraoxon at a rate approaching the diffusion limit and thus appears to be optimally evolved for utilizing this synthetic substrate.
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| __TOC__
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| </StructureSection>
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| [[Category: Aryldialkylphosphatase]]
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| [[Category: Large Structures]]
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| [[Category: Aggarwal, N]]
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| [[Category: Albeck, S]]
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| [[Category: Ashani, Y]]
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| [[Category: Dym, O]]
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| [[Category: Goldsmith, M]]
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| [[Category: Greisen, P]]
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| [[Category: Leader, H]]
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| [[Category: Rogotner, S Hamer]]
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| [[Category: Silman, I]]
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| [[Category: Sussman, L J]]
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| [[Category: Tawfik, D]]
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| [[Category: Unger, T]]
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| [[Category: Hydrolase]]
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| [[Category: Metalloenzyme]]
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| [[Category: Tim barrel]]
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This PDB entry is obsolete and replaced by 8p7r
