7yfd: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 7yfd is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7yfd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YFD OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7YFD FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=ITF:2-(1~{H}-imidazol-5-yl)ethyl+carbamimidothioate'>ITF</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7yfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yfd OCA], [https://pdbe.org/7yfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yfd RCSB], [https://www.ebi.ac.uk/pdbsum/7yfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yfd ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Lama glama]]

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Dohyun I]]

[[Category: Hidetsugu A]]

[[Category: So I]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7yfd is ON HOLD  until Paper Publication
+==Cryo-EM structure of the imetit-bound histamine H4 receptor and Gq complex==
+<StructureSection load='7yfd' size='340' side='right'caption='[[7yfd]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7yfd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YFD FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=ITF:2-(1~{H}-imidazol-5-yl)ethyl+carbamimidothioate'>ITF</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yfd OCA], [https://pdbe.org/7yfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yfd RCSB], [https://www.ebi.ac.uk/pdbsum/7yfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yfd ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Lama glama]]
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Dohyun I]]
+[[Category: Hidetsugu A]]
+[[Category: So I]]