1ubc: Difference between revisions
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<StructureSection load='1ubc' size='340' side='right'caption='[[1ubc]], [[Resolution|resolution]] 3.80Å' scene=''> | <StructureSection load='1ubc' size='340' side='right'caption='[[1ubc]], [[Resolution|resolution]] 3.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ubc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1ubc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UBC FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ubc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ubc OCA], [https://pdbe.org/1ubc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ubc RCSB], [https://www.ebi.ac.uk/pdbsum/1ubc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ubc ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ubc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ubc OCA], [https://pdbe.org/1ubc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ubc RCSB], [https://www.ebi.ac.uk/pdbsum/1ubc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ubc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/RECA_MYCS2 RECA_MYCS2] Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the effect of nucleotide binding to the DNA-binding region.<ref>PMID:17360246</ref> <ref>PMID:17496093</ref> <ref>PMID:21219454</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[ | *[[3D structures of recombinase A|3D structures of recombinase A]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chandra | [[Category: Mycolicibacterium smegmatis]] | ||
[[Category: Datta | [[Category: Chandra NR]] | ||
[[Category: Ganesh | [[Category: Datta S]] | ||
[[Category: Krishna | [[Category: Ganesh N]] | ||
[[Category: Muniyappa | [[Category: Krishna R]] | ||
[[Category: Vijayan | [[Category: Muniyappa K]] | ||
[[Category: Vijayan M]] | |||
