1wkm: Difference between revisions

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<StructureSection load='1wkm' size='340' side='right'caption='[[1wkm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1wkm' size='340' side='right'caption='[[1wkm]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1wkm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKM FirstGlance]. <br>
<table><tr><td colspan='2'>[[1wkm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xgm|1xgm]], [[1xgn|1xgn]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkm OCA], [https://pdbe.org/1wkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkm RCSB], [https://www.ebi.ac.uk/pdbsum/1wkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkm OCA], [https://pdbe.org/1wkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkm RCSB], [https://www.ebi.ac.uk/pdbsum/1wkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/AMPM_PYRFU AMPM_PYRFU]] Removes the N-terminal methionine from nascent proteins.  
[https://www.uniprot.org/uniprot/MAP2_PYRFU MAP2_PYRFU] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).[HAMAP-Rule:MF_01975]<ref>PMID:9399590</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43587]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Methionyl aminopeptidase]]
[[Category: Pyrococcus furiosus]]
[[Category: Bennett, B]]
[[Category: Bennett B]]
[[Category: Copik, A J]]
[[Category: Copik AJ]]
[[Category: Holz, R C]]
[[Category: D'souza VM]]
[[Category: Jang, S B]]
[[Category: Holz RC]]
[[Category: Meng, L]]
[[Category: Jang SB]]
[[Category: Nocek, B P]]
[[Category: Meng L]]
[[Category: Peters, J W]]
[[Category: Nocek BP]]
[[Category: Ruebush, S]]
[[Category: Peters JW]]
[[Category: Swierczek, S I]]
[[Category: Ruebush S]]
[[Category: Souza, V M.D]]
[[Category: Swierczek SI]]
[[Category: Aminopeptidase]]
[[Category: Hydrolase]]
[[Category: Hyperthermophile]]
[[Category: Methionine complex]]
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