2dwl: Difference between revisions
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<StructureSection load='2dwl' size='340' side='right'caption='[[2dwl]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='2dwl' size='340' side='right'caption='[[2dwl]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2dwl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2dwl]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DWL FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dwl OCA], [https://pdbe.org/2dwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dwl RCSB], [https://www.ebi.ac.uk/pdbsum/2dwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dwl ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dwl OCA], [https://pdbe.org/2dwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dwl RCSB], [https://www.ebi.ac.uk/pdbsum/2dwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dwl ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PRIA_ECOLI PRIA_ECOLI] Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. Is also involved in initiation of normal DNA replication in various plasmids and phages. Binds to branched DNA structures that resemble D-loops or to the primosome assembly site (PAS). Binds to DNA in two distinct modes, either dependent on or independent of the 3' terminus recognition.<ref>PMID:2825188</ref> <ref>PMID:8366072</ref> <ref>PMID:10356325</ref> <ref>PMID:10956036</ref> <ref>PMID:11929519</ref> <ref>PMID:12622722</ref> <ref>PMID:12917421</ref> <ref>PMID:15576682</ref> <ref>PMID:17483094</ref> <ref>PMID:23264623</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kohda | [[Category: Kohda D]] | ||
[[Category: Maenaka | [[Category: Maenaka K]] | ||
[[Category: Masai | [[Category: Masai H]] | ||
[[Category: Ose | [[Category: Ose T]] | ||
[[Category: Sasaki | [[Category: Sasaki K]] | ||
[[Category: Tanaka | [[Category: Tanaka T]] | ||
