2e99: Difference between revisions

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<StructureSection load='2e99' size='340' side='right'caption='[[2e99]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2e99' size='340' side='right'caption='[[2e99]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2e99]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E99 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2e99]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E99 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B08:(1-HYDROXY-1-PHOSPHONO-2-[1,1;3,1]TERPHENYL-3-YL-ETHYL)-PHOSPHONIC+ACID'>B08</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1x06|1x06]], [[1x07|1x07]], [[1x08|1x08]], [[1x09|1x09]], [[2e98|2e98]], [[2e9a|2e9a]], [[2e9c|2e9c]], [[2e9d|2e9d]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B08:(1-HYDROXY-1-PHOSPHONO-2-[1,1;3,1]TERPHENYL-3-YL-ETHYL)-PHOSPHONIC+ACID'>B08</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ditrans,polycis-undecaprenyl-diphosphate_synthase_((2E,6E)-farnesyl-_diphosphate_specific) Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl- diphosphate specific)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.31 2.5.1.31] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e99 OCA], [https://pdbe.org/2e99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e99 RCSB], [https://www.ebi.ac.uk/pdbsum/2e99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e99 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e99 OCA], [https://pdbe.org/2e99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e99 RCSB], [https://www.ebi.ac.uk/pdbsum/2e99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e99 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI]] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>
[https://www.uniprot.org/uniprot/UPPS_ECOLI UPPS_ECOLI] Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate (FPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<ref>PMID:12756244</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cao, R]]
[[Category: Cao R]]
[[Category: Guo, R T]]
[[Category: Guo RT]]
[[Category: Ko, T P]]
[[Category: Ko TP]]
[[Category: Liang, P H]]
[[Category: Liang PH]]
[[Category: Oldfield, E]]
[[Category: Oldfield E]]
[[Category: Wang, A H.J]]
[[Category: Wang AHJ]]
[[Category: Antibiotic]]
[[Category: Bisphosphonate]]
[[Category: Cell wall]]
[[Category: Farnesyl pyrophosphate]]
[[Category: Prenyltransferase]]
[[Category: Transferase]]
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