2pd4: Difference between revisions

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<StructureSection load='2pd4' size='340' side='right'caption='[[2pd4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2pd4' size='340' side='right'caption='[[2pd4]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pd4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jw7 1jw7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PD4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pd4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1jw7 1jw7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PD4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PD4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCN:DICLOSAN'>DCN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2pd3|2pd3]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DCN:DICLOSAN'>DCN</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pd4 OCA], [https://pdbe.org/2pd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pd4 RCSB], [https://www.ebi.ac.uk/pdbsum/2pd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pd4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pd4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pd4 OCA], [https://pdbe.org/2pd4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pd4 RCSB], [https://www.ebi.ac.uk/pdbsum/2pd4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pd4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FABI_HELPY FABI_HELPY]] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).  
[https://www.uniprot.org/uniprot/FABI_HELPY FABI_HELPY] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 43504]]
[[Category: Helicobacter pylori]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lee, H H]]
[[Category: Lee HH]]
[[Category: Moon, J H]]
[[Category: Moon JH]]
[[Category: Suh, S W]]
[[Category: Suh SW]]
[[Category: Antibacterial target]]
[[Category: Enoyl-acp-reductase]]
[[Category: Fabi]]
[[Category: Helicobacter pylori]]
[[Category: Oxidoreductase]]
[[Category: Type ii fatty acid biosynthesis]]