2r90: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2r90]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R90 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2r90]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R90 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yck|1yck]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r90 OCA], [https://pdbe.org/2r90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r90 RCSB], [https://www.ebi.ac.uk/pdbsum/2r90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r90 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r90 OCA], [https://pdbe.org/2r90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r90 RCSB], [https://www.ebi.ac.uk/pdbsum/2r90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r90 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR]] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).  
[https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Camelus dromedarius]]
[[Category: Camelus dromedarius]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kaur, P]]
[[Category: Kaur P]]
[[Category: Sharma, P]]
[[Category: Sharma P]]
[[Category: Sharma, S]]
[[Category: Sharma S]]
[[Category: Singh, N]]
[[Category: Singh N]]
[[Category: Singh, T P]]
[[Category: Singh TP]]
[[Category: Sinha, M]]
[[Category: Sinha M]]
[[Category: Srinivasan, A]]
[[Category: Srinivasan A]]
[[Category: Anti bacterial activity]]
[[Category: Antibiotic]]
[[Category: Antimicrobial]]
[[Category: Immune response]]
[[Category: Immune system]]
[[Category: Secreted]]

Revision as of 09:03, 25 October 2023

Crystal structure of cameline peptidoglycan recognition protein at 2.8A resolution

2r90, resolution 2.80Å

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