8bhq: Difference between revisions
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==GABA-A receptor a5 homomer - a5V3 - RO7172670== | |||
<StructureSection load='8bhq' size='340' side='right'caption='[[8bhq]], [[Resolution|resolution]] 3.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8bhq]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BHQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=QR3:2-[[5-methyl-3-(6-methylpyridazin-3-yl)-1,2-oxazol-4-yl]methyl]-5-(5-oxa-2-azaspiro[3.5]nonan-2-yl)pyridazin-3-one'>QR3</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bhq OCA], [https://pdbe.org/8bhq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bhq RCSB], [https://www.ebi.ac.uk/pdbsum/8bhq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bhq ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GBRA5_HUMAN GBRA5_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hardwick SW]] | |||
[[Category: Kasaragod VB]] | |||
[[Category: Malinauskas TM]] | |||
[[Category: Miller PS]] | |||
Revision as of 13:03, 1 November 2023
GABA-A receptor a5 homomer - a5V3 - RO7172670
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