8pjb: Difference between revisions
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==Cryo-EM structure of MLE in complex with UUC RNA and ADP== | |||
<StructureSection load='8pjb' size='340' side='right'caption='[[8pjb]], [[Resolution|resolution]] 3.62Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8pjb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PJB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.62Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
[[Category: Hennig | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pjb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pjb OCA], [https://pdbe.org/8pjb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pjb RCSB], [https://www.ebi.ac.uk/pdbsum/8pjb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pjb ProSAT]</span></td></tr> | ||
[[Category: Jagtap | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MLE_DROME MLE_DROME] Required in males for dosage compensation of X chromosome linked genes. Mle, msl-1 and msl-3 are colocalized on X chromosome. Each of the msl proteins requires all the other msls for wild-type X-chromosome binding. Probably unwinds double-stranded DNA and RNA in a 3' to 5' direction.<ref>PMID:1653648</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Large Structures]] | |||
[[Category: Hennig J]] | |||
[[Category: Jagtap PKA]] | |||
Revision as of 13:11, 1 November 2023
Cryo-EM structure of MLE in complex with UUC RNA and ADP
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