2zgl: Difference between revisions

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<StructureSection load='2zgl' size='340' side='right'caption='[[2zgl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2zgl' size='340' side='right'caption='[[2zgl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zgl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrae Agrae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZGL FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zgl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cyclocybe_aegerita Cyclocybe aegerita]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZGL FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zgk|2zgk]], [[2zgm|2zgm]], [[2zgn|2zgn]], [[2zgo|2zgo]], [[2zgp|2zgp]], [[2zgq|2zgq]], [[2zgr|2zgr]], [[2zgs|2zgs]], [[2zgt|2zgt]], [[2zgu|2zgu]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AAL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5400 AGRAE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zgl OCA], [https://pdbe.org/2zgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zgl RCSB], [https://www.ebi.ac.uk/pdbsum/2zgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zgl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zgl OCA], [https://pdbe.org/2zgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zgl RCSB], [https://www.ebi.ac.uk/pdbsum/2zgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zgl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ATLE_AGRAE ATLE_AGRAE]] Anti-tumor lectin with DNase activity. Inhibits the growth of several tumor cell lines in vitro. Induces lymphocyte infiltration and necrosis of tumor cells in a mouse tumor model. Induces apoptosis in HeLa cells.<ref>PMID:12757412</ref>
[https://www.uniprot.org/uniprot/ATLE_CYCAE ATLE_CYCAE] Anti-tumor lectin with DNase activity. Inhibits the growth of several tumor cell lines in vitro. Induces lymphocyte infiltration and necrosis of tumor cells in a mouse tumor model. Induces apoptosis in HeLa cells. Binds N-acetylneuraminyl lactose (N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucose) (PubMed:16051274).<ref>PMID:12757412</ref> <ref>PMID:16051274</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Agrae]]
[[Category: Cyclocybe aegerita]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Li, D F]]
[[Category: Li DF]]
[[Category: Wang, D C]]
[[Category: Wang DC]]
[[Category: Yang, N]]
[[Category: Yang N]]
[[Category: Apoptosis]]
[[Category: Galectin]]
[[Category: Hydrolase]]
[[Category: Jelly roll]]
[[Category: Nuclease]]
Retrieved from "https://proteopedia.org/2zgl"