2zin: Difference between revisions

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<StructureSection load='2zin' size='340' side='right'caption='[[2zin]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='2zin' size='340' side='right'caption='[[2zin]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zin]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dsm_2053 Dsm 2053]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZIN FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zin]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZIN FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=LBY:N~6~-(TERT-BUTOXYCARBONYL)-L-LYSINE'>LBY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2e3c|2e3c]], [[2zcd|2zcd]], [[2zce|2zce]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=LBY:N~6~-(TERT-BUTOXYCARBONYL)-L-LYSINE'>LBY</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pylS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 DSM 2053])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyrrolysine--tRNA(Pyl)_ligase Pyrrolysine--tRNA(Pyl) ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.26 6.1.1.26] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zin OCA], [https://pdbe.org/2zin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zin RCSB], [https://www.ebi.ac.uk/pdbsum/2zin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zin ProSAT], [https://www.topsan.org/Proteins/RSGI/2zin TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zin OCA], [https://pdbe.org/2zin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zin RCSB], [https://www.ebi.ac.uk/pdbsum/2zin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zin ProSAT], [https://www.topsan.org/Proteins/RSGI/2zin TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA]] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).  
[https://www.uniprot.org/uniprot/PYLS_METMA PYLS_METMA] Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Dsm 2053]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ishii, R]]
[[Category: Methanosarcina mazei]]
[[Category: Structural genomic]]
[[Category: Ishii R]]
[[Category: Yanagisawa, T]]
[[Category: Yanagisawa T]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Atp analogue]]
[[Category: Atp-binding]]
[[Category: Cytoplasm]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Non-natural amino acid]]
[[Category: Nppsfa]]
[[Category: Nucleotide-binding]]
[[Category: Protein biosynthesis]]
[[Category: Pyrrolysine]]
[[Category: Pyrrolysyl-trna synthetase]]
[[Category: Rsgi]]
[[Category: Trna]]
[[Category: Unnatural amino acid]]