2zqp: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
Line 3: Line 3:
<StructureSection load='2zqp' size='340' side='right'caption='[[2zqp]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
<StructureSection load='2zqp' size='340' side='right'caption='[[2zqp]], [[Resolution|resolution]] 6.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2zqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2zqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQP FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2zjs|2zjs]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 6&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqp OCA], [https://pdbe.org/2zqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqp RCSB], [https://www.ebi.ac.uk/pdbsum/2zqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqp OCA], [https://pdbe.org/2zqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqp RCSB], [https://www.ebi.ac.uk/pdbsum/2zqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/Q8KZP3_THETH Q8KZP3_THETH]] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity).[HAMAP-Rule:MF_01465] [[https://www.uniprot.org/uniprot/Q8KZP4_THETH Q8KZP4_THETH]] Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation (By similarity).[HAMAP-Rule:MF_00422]
[https://www.uniprot.org/uniprot/SECY_THET8 SECY_THET8] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 30: Line 30:


==See Also==
==See Also==
*[[Preprotein translocase|Preprotein translocase]]
*[[Preprotein translocase 3D structures|Preprotein translocase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Nureki, O]]
[[Category: Thermus thermophilus]]
[[Category: Tsukazaki, T]]
[[Category: Nureki O]]
[[Category: Membrane]]
[[Category: Tsukazaki T]]
[[Category: Protein transport]]
[[Category: Protein-conducting-channel]]
[[Category: Sec]]
[[Category: Translocation]]
[[Category: Translocon]]
[[Category: Transmembrane]]
[[Category: Transport]]