3d55: Difference between revisions

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<StructureSection load='3d55' size='340' side='right'caption='[[3d55]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
<StructureSection load='3d55' size='340' side='right'caption='[[3d55]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3d55]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D55 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3d55]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D55 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3cto|3cto]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv3357, MT3465, MTV004.14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d55 OCA], [https://pdbe.org/3d55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d55 RCSB], [https://www.ebi.ac.uk/pdbsum/3d55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d55 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d55 OCA], [https://pdbe.org/3d55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d55 RCSB], [https://www.ebi.ac.uk/pdbsum/3d55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d55 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RELJ_MYCTU RELJ_MYCTU]] Antitoxin component of a toxin-antitoxin (TA) module. A probable antitoxin for the putative mRNA interferase RelK. Upon expression in E.coli but not in M.smegmatis this protein neutralizes E.coli YoeB.  Binds to and represses its own promoter, in combination with RelK repression is somewhat lessened. Several DNA-protein complexes are formed in vitro depending on the RelJ:RelK ratio.  
[https://www.uniprot.org/uniprot/RELJ_MYCTU RELJ_MYCTU] Antitoxin component of a toxin-antitoxin (TA) module. A probable antitoxin for the putative mRNA interferase RelK. Upon expression in E.coli but not in M.smegmatis this protein neutralizes E.coli YoeB.  Binds to and represses its own promoter, in combination with RelK repression is somewhat lessened. Several DNA-protein complexes are formed in vitro depending on the RelJ:RelK ratio.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dodson, E J]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Issac, B]]
[[Category: Dodson EJ]]
[[Category: Kumar, P]]
[[Category: Issac B]]
[[Category: Mande, S C]]
[[Category: Kumar P]]
[[Category: Turkenberg, J P]]
[[Category: Mande SC]]
[[Category: Tetramer]]
[[Category: Turkenberg JP]]
[[Category: Toxin inhibitor]]
[[Category: Toxin neutraliser]]