3i9l: Difference between revisions

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<StructureSection load='3i9l' size='340' side='right'caption='[[3i9l]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='3i9l' size='340' side='right'caption='[[3i9l]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3i9l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplca Aplca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I9L FirstGlance]. <br>
<table><tr><td colspan='2'>[[3i9l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aplysia_californica Aplysia californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I9L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I9L FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N1C:N1-CYCLIC+INOSINE+5-DIPHOSPHORIBOSE'>N1C</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3i9j|3i9j]], [[3i9k|3i9k]], [[3i9m|3i9m]], [[3i9n|3i9n]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N1C:N1-CYCLIC+INOSINE+5-DIPHOSPHORIBOSE'>N1C</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NAD(+)_nucleosidase NAD(+) nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.5 3.2.2.5] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i9l OCA], [https://pdbe.org/3i9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i9l RCSB], [https://www.ebi.ac.uk/pdbsum/3i9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i9l ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i9l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i9l OCA], [https://pdbe.org/3i9l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i9l RCSB], [https://www.ebi.ac.uk/pdbsum/3i9l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i9l ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA]] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref>
[https://www.uniprot.org/uniprot/NADA_APLCA NADA_APLCA] Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for calcium mobilization from endoplasmic reticulum. Also has cADPr hydrolase activity.<ref>PMID:11829748</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Aplca]]
[[Category: Aplysia californica]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Graeff, R]]
[[Category: Graeff R]]
[[Category: Hao, Q]]
[[Category: Hao Q]]
[[Category: Jiang, H]]
[[Category: Jiang H]]
[[Category: Kriksunov, I A]]
[[Category: Kriksunov IA]]
[[Category: Lee, H C]]
[[Category: Lee HC]]
[[Category: Lin, H]]
[[Category: Lin H]]
[[Category: Liu, Q]]
[[Category: Liu Q]]
[[Category: Oppenheimer, N]]
[[Category: Oppenheimer N]]
[[Category: Potter, B V.L]]
[[Category: Potter BVL]]
[[Category: Zhang, B]]
[[Category: Zhang B]]
[[Category: Adp-ribosyl cyclase]]
[[Category: Disulfide bond]]
[[Category: Enzyme-product analog complex]]
[[Category: Fertilization]]
[[Category: Homodimer]]
[[Category: Hydrolase]]
[[Category: Nad]]
Retrieved from "https://proteopedia.org/3i9l"