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==Structural basis for the negative regulation of bacterial stress response by RseB==
==Structural basis for the negative regulation of bacterial stress response by RseB==
<StructureSection load='3m4w' size='340' side='right' caption='[[3m4w]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3m4w' size='340' side='right'caption='[[3m4w]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3m4w]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M4W FirstGlance]. <br>
<table><tr><td colspan='2'>[[3m4w]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M4W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2p4b|2p4b]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RseB (Amino Acids 24-318) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), RseA (Amino Acids 121-216) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4w OCA], [https://pdbe.org/3m4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m4w RCSB], [https://www.ebi.ac.uk/pdbsum/3m4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4w OCA], [http://pdbe.org/3m4w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m4w RCSB], [http://www.ebi.ac.uk/pdbsum/3m4w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RSEB_ECOLI RSEB_ECOLI]] Seems to modulate the activity of RpoE (sigma-E). [[http://www.uniprot.org/uniprot/RSEA_ECOLI RSEA_ECOLI]] Negative regulator of RpoE.  
[https://www.uniprot.org/uniprot/RSEB_ECOLI RSEB_ECOLI] Seems to modulate the activity of RpoE (sigma-E).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Choi, J K]]
[[Category: Large Structures]]
[[Category: Hwang, H Y]]
[[Category: Choi JK]]
[[Category: Kim, D Y]]
[[Category: Hwang H-Y]]
[[Category: Kim, K K]]
[[Category: Kim DY]]
[[Category: Kwon, E]]
[[Category: Kim KK]]
[[Category: Cell membrane]]
[[Category: Kwon E]]
[[Category: Periplasm]]
[[Category: Rsea]]
[[Category: Rseb]]
[[Category: Rsep]]
[[Category: Sigma factor]]
[[Category: Signaling protein-signaling protein complex]]
[[Category: Stress response]]
[[Category: Transmembrane]]

Latest revision as of 16:29, 1 November 2023

Structural basis for the negative regulation of bacterial stress response by RseB

3m4w, resolution 2.30Å

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