3tb5: Difference between revisions

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<StructureSection load='3tb5' size='340' side='right'caption='[[3tb5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3tb5' size='340' side='right'caption='[[3tb5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tb5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_hip11704 Enterococcus faecalis hip11704]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TB5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tb5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis_HIP11704 Enterococcus faecalis HIP11704]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TB5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EFHG_00941, MetAP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=565646 Enterococcus faecalis HIP11704])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tb5 OCA], [https://pdbe.org/3tb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tb5 RCSB], [https://www.ebi.ac.uk/pdbsum/3tb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tb5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tb5 OCA], [https://pdbe.org/3tb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tb5 RCSB], [https://www.ebi.ac.uk/pdbsum/3tb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tb5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/C7VIN6_ENTFL C7VIN6_ENTFL]] Removes the N-terminal methionine from nascent proteins.[RuleBase:RU003653]  Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[HAMAP-Rule:MF_01974]


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Enterococcus faecalis hip11704]]
[[Category: Enterococcus faecalis HIP11704]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Methionyl aminopeptidase]]
[[Category: Addlagatta A]]
[[Category: Addlagatta, A]]
[[Category: Gumpena R]]
[[Category: Gumpena, R]]
[[Category: Kishor C]]
[[Category: Kishor, C]]
[[Category: Reddi R]]
[[Category: Reddi, R]]
[[Category: Enterococcus feacali]]
[[Category: Hydrolase]]
[[Category: Metalloprotease]]
[[Category: Methionine aminopeptidase]]

Latest revision as of 17:30, 1 November 2023

Crystal Structure of the Enterococcus faecalis Methionine aminopeptidase apo form

3tb5, resolution 2.30Å

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