3tjv: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='3tjv' size='340' side='right'caption='[[3tjv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3tjv' size='340' side='right'caption='[[3tjv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tjv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TJV FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tjv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TJV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3tju|3tju]], [[3tk9|3tk9]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GZMH, CGL2, CTSGL2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tjv OCA], [https://pdbe.org/3tjv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tjv RCSB], [https://www.ebi.ac.uk/pdbsum/3tjv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tjv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tjv OCA], [https://pdbe.org/3tjv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tjv RCSB], [https://www.ebi.ac.uk/pdbsum/3tjv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tjv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/GRAH_HUMAN GRAH_HUMAN]] Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.<ref>PMID:22156497</ref> <ref>PMID:23269243</ref>
[https://www.uniprot.org/uniprot/GRAH_HUMAN GRAH_HUMAN] Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.<ref>PMID:22156497</ref> <ref>PMID:23269243</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Fan, Z]]
[[Category: Fan Z]]
[[Category: Sun, F]]
[[Category: Sun F]]
[[Category: Tong, L]]
[[Category: Tong L]]
[[Category: Wang, L]]
[[Category: Wang L]]
[[Category: Wu, L]]
[[Category: Wu L]]
[[Category: Zhang, K]]
[[Category: Zhang K]]
[[Category: Cytolysis]]
[[Category: Hydrolase]]
[[Category: Hydrolase substrate]]
[[Category: Serine protease]]
Retrieved from "https://proteopedia.org/3tjv"