5m42: Difference between revisions

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<StructureSection load='5m42' size='340' side='right'caption='[[5m42]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='5m42' size='340' side='right'caption='[[5m42]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5m42]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet2 Thet2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M42 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M42 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5m42]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M42 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M42 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TT_C1214 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=262724 THET2])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Proline_dehydrogenase Proline dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.5.2 1.5.5.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m42 OCA], [https://pdbe.org/5m42 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m42 RCSB], [https://www.ebi.ac.uk/pdbsum/5m42 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m42 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m42 OCA], [http://pdbe.org/5m42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m42 RCSB], [http://www.ebi.ac.uk/pdbsum/5m42 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m42 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRODH_THET2 PRODH_THET2]] Converts proline to delta-1-pyrroline-5-carboxylate (PubMed:17344208, PubMed:18426222). Has significant activity against O(2) producing superoxide during proline oxidation catalytic cycle (PubMed:17344208).<ref>PMID:17344208</ref> <ref>PMID:18426222</ref>
[https://www.uniprot.org/uniprot/PRODH_THET2 PRODH_THET2] Converts proline to delta-1-pyrroline-5-carboxylate (PubMed:17344208, PubMed:18426222). Has significant activity against O(2) producing superoxide during proline oxidation catalytic cycle (PubMed:17344208).<ref>PMID:17344208</ref> <ref>PMID:18426222</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Proline dehydrogenase]]
[[Category: Thermus thermophilus HB27]]
[[Category: Thet2]]
[[Category: Huijbers MME]]
[[Category: Berkel, W J.H van]]
[[Category: Martinez-Julvez M]]
[[Category: Huijbers, M M.E]]
[[Category: Medina M]]
[[Category: Martinez-Julvez, M]]
[[Category: Van Berkel WJH]]
[[Category: Medina, M]]
[[Category: Beta8-alpha8-barrel]]
[[Category: Flavoenzyme]]
[[Category: Oxidoreductase]]