5mec: Difference between revisions

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==Crystal structure of yeast Cdt1 middle domain (residues 294-433)==
==Crystal structure of yeast Cdt1 middle domain (residues 294-433)==
<StructureSection load='5mec' size='340' side='right' caption='[[5mec]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
<StructureSection load='5mec' size='340' side='right'caption='[[5mec]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MEC FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MEC FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TAH11, CDT1, SID2, YJR046W, J1641 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mec OCA], [http://pdbe.org/5mec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mec RCSB], [http://www.ebi.ac.uk/pdbsum/5mec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mec ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mec OCA], [https://pdbe.org/5mec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mec RCSB], [https://www.ebi.ac.uk/pdbsum/5mec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mec ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CDT1_YEAST CDT1_YEAST]] DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins.<ref>PMID:11560884</ref> <ref>PMID:11967159</ref> <ref>PMID:16387651</ref> <ref>PMID:16824194</ref> <ref>PMID:17825064</ref> <ref>PMID:18006685</ref> <ref>PMID:19896182</ref>
[https://www.uniprot.org/uniprot/CDT1_YEAST CDT1_YEAST] DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins.<ref>PMID:11560884</ref> <ref>PMID:11967159</ref> <ref>PMID:16387651</ref> <ref>PMID:16824194</ref> <ref>PMID:17825064</ref> <ref>PMID:18006685</ref> <ref>PMID:19896182</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 18824]]
[[Category: Large Structures]]
[[Category: Cherepanov, P]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Diffley, J F.X]]
[[Category: Cherepanov P]]
[[Category: Frigola, J]]
[[Category: Diffley JFX]]
[[Category: Pye, V E]]
[[Category: Frigola J]]
[[Category: Cdt1]]
[[Category: Pye VE]]
[[Category: Cell cycle]]
[[Category: Dna replication]]
[[Category: Mcm]]
[[Category: Winged helix]]
[[Category: Yeast]]