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==Designed armadillo repeat protein YIIIM''6AII in complex with pD_(KR)5==
==Designed armadillo repeat protein YIIIM''6AII in complex with pD_(KR)5==
<StructureSection load='5mfd' size='340' side='right' caption='[[5mfd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5mfd' size='340' side='right'caption='[[5mfd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mfd]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MFD FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mfd]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MFD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">D, lambdap07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfd OCA], [http://pdbe.org/5mfd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mfd RCSB], [http://www.ebi.ac.uk/pdbsum/5mfd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfd ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mfd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mfd OCA], [https://pdbe.org/5mfd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mfd RCSB], [https://www.ebi.ac.uk/pdbsum/5mfd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mfd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DECO_LAMBD DECO_LAMBD]] Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell.<ref>PMID:18786402</ref> <ref>PMID:21821043</ref> <ref>PMID:8411174</ref>
[https://www.uniprot.org/uniprot/DECO_LAMBD DECO_LAMBD] Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell.<ref>PMID:18786402</ref> <ref>PMID:21821043</ref> <ref>PMID:8411174</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage lambda]]
[[Category: Escherichia virus Lambda]]
[[Category: Synthetic construct sequences]]
[[Category: Large Structures]]
[[Category: Hansen, S]]
[[Category: Synthetic construct]]
[[Category: Kiefer, J]]
[[Category: Hansen S]]
[[Category: Madhurantakam, C]]
[[Category: Kiefer J]]
[[Category: Mittl, P]]
[[Category: Madhurantakam C]]
[[Category: Plueckthun, A]]
[[Category: Mittl P]]
[[Category: De novo protein]]
[[Category: Plueckthun A]]
[[Category: Designed armadillo repeat protein]]
[[Category: Peptide binding]]
Retrieved from "https://proteopedia.org/5mfd"