5mkt: Difference between revisions

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<StructureSection load='5mkt' size='340' side='right'caption='[[5mkt]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='5mkt' size='340' side='right'caption='[[5mkt]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MKT OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MKT FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MKT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ren1, Ren, Ren-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mkt OCA], [https://pdbe.org/5mkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mkt RCSB], [https://www.ebi.ac.uk/pdbsum/5mkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mkt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mkt OCA], [http://pdbe.org/5mkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mkt RCSB], [http://www.ebi.ac.uk/pdbsum/5mkt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mkt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RENI1_MOUSE RENI1_MOUSE]] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.  
[https://www.uniprot.org/uniprot/RENI1_MOUSE RENI1_MOUSE] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Renin]]
[[Category: Read R]]
[[Category: Read, R]]
[[Category: Yan Y]]
[[Category: Yan, Y]]
[[Category: Hydrolase]]
[[Category: Prorenin]]

Latest revision as of 18:48, 1 November 2023

Crystal structure of mouse prorenin

5mkt, resolution 3.20Å

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