3v66: Difference between revisions

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<StructureSection load='3v66' size='340' side='right'caption='[[3v66]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3v66' size='340' side='right'caption='[[3v66]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3v66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V66 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3v66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V66 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D3A:(1-{[(4R,6S)-8-CHLORO-6-(2,3-DIMETHOXYPHENYL)-4H,6H-PYRROLO[1,2-A][4,1]BENZOXAZEPIN-4-YL]ACETYL}PIPERIDIN-4-YL)ACETIC+ACID'>D3A</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q30|3q30]], [[3asx|3asx]], [[3q2z|3q2z]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D3A:(1-{[(4R,6S)-8-CHLORO-6-(2,3-DIMETHOXYPHENYL)-4H,6H-PYRROLO[1,2-A][4,1]BENZOXAZEPIN-4-YL]ACETYL}PIPERIDIN-4-YL)ACETIC+ACID'>D3A</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDFT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v66 OCA], [https://pdbe.org/3v66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v66 RCSB], [https://www.ebi.ac.uk/pdbsum/3v66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v66 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v66 OCA], [https://pdbe.org/3v66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v66 RCSB], [https://www.ebi.ac.uk/pdbsum/3v66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v66 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FDFT_HUMAN FDFT_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Squalene synthase]]
[[Category: Haginoya N]]
[[Category: Haginoya, N]]
[[Category: Higashihashi N]]
[[Category: Higashihashi, N]]
[[Category: Ichikawa M]]
[[Category: Ichikawa, M]]
[[Category: Itoh M]]
[[Category: Itoh, M]]
[[Category: Ohki H]]
[[Category: Ohki, H]]
[[Category: Ohtsuka M]]
[[Category: Ohtsuka, M]]
[[Category: Sugita K]]
[[Category: Sugita, K]]
[[Category: Suzuki M]]
[[Category: Suzuki, M]]
[[Category: Usui H]]
[[Category: Usui, H]]
[[Category: Isoprene biosynthesis]]
[[Category: Lipid synthesis]]
[[Category: Multifunctional enzyme]]
[[Category: Oxidoreductase]]
[[Category: Steroid biosynthesis]]
[[Category: Sterol biosynthesis]]
[[Category: Terpenoid synthase fold]]
[[Category: Transferase-transferase inhibitor complex]]
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