3vl1: Difference between revisions

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<StructureSection load='3vl1' size='340' side='right'caption='[[3vl1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3vl1' size='340' side='right'caption='[[3vl1]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3vl1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VL1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3vl1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VL1 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3acp|3acp]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RPN14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vl1 OCA], [https://pdbe.org/3vl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vl1 RCSB], [https://www.ebi.ac.uk/pdbsum/3vl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vl1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vl1 OCA], [https://pdbe.org/3vl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vl1 RCSB], [https://www.ebi.ac.uk/pdbsum/3vl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vl1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RPN14_YEAST RPN14_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Is not a genuine component of the 26S proteasome, but an auxiliary factor that interacts with the proteasomal ATPase of 19S regulatory particle (RP). Acts as a chaperone which regulates the highly structured assembly of the 19S regulatory particle. Involved in the substrate specificity of the 26S proteasome and is especially involved in the degradation of ubiquitinated GCN4. May contribute to the stability of the 26S proteasome in some stress conditions.<ref>PMID:17499717</ref> <ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:19446323</ref>
[https://www.uniprot.org/uniprot/RPN14_YEAST RPN14_YEAST] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Is not a genuine component of the 26S proteasome, but an auxiliary factor that interacts with the proteasomal ATPase of 19S regulatory particle (RP). Acts as a chaperone which regulates the highly structured assembly of the 19S regulatory particle. Involved in the substrate specificity of the 26S proteasome and is especially involved in the degradation of ubiquitinated GCN4. May contribute to the stability of the 26S proteasome in some stress conditions.<ref>PMID:17499717</ref> <ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:19446323</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kato, K]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Kim, S]]
[[Category: Kato K]]
[[Category: Mizushima, T]]
[[Category: Kim S]]
[[Category: Nishide, A]]
[[Category: Mizushima T]]
[[Category: Saeki, Y]]
[[Category: Nishide A]]
[[Category: Takagi, K]]
[[Category: Saeki Y]]
[[Category: Tanaka, K]]
[[Category: Takagi K]]
[[Category: Beta-propeller]]
[[Category: Tanaka K]]
[[Category: Chaperone]]
[[Category: Rpt6]]
Retrieved from "https://proteopedia.org/3vl1"