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==Structure of human apo-SRP72==
==Structure of human apo-SRP72==
<StructureSection load='5wrw' size='340' side='right' caption='[[5wrw]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
<StructureSection load='5wrw' size='340' side='right'caption='[[5wrw]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5wrw]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WRW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WRW FirstGlance]. <br>
<table><tr><td colspan='2'>[[5wrw]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WRW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WRW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SRP72 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wrw OCA], [http://pdbe.org/5wrw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wrw RCSB], [http://www.ebi.ac.uk/pdbsum/5wrw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wrw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wrw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wrw OCA], [https://pdbe.org/5wrw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wrw RCSB], [https://www.ebi.ac.uk/pdbsum/5wrw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wrw ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/SRP72_HUMAN SRP72_HUMAN]] Autosomal dominant aplasia and myelodysplasia. The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/SRP72_HUMAN SRP72_HUMAN] Autosomal dominant aplasia and myelodysplasia. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SRP72_HUMAN SRP72_HUMAN]] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.  
[https://www.uniprot.org/uniprot/SRP72_HUMAN SRP72_HUMAN] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5wrw" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5wrw" style="background-color:#fffaf0;"></div>
==See Also==
*[[Signal recognition particle protein|Signal recognition particle protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Chen, Z]]
[[Category: Large Structures]]
[[Category: Gao, Y]]
[[Category: Chen Z]]
[[Category: Complex]]
[[Category: Gao Y]]
[[Category: Protein transport]]
[[Category: Signal recognition particle]]
[[Category: Srp68]]
[[Category: Srp72]]
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