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==Solution NMR Structure of BCMA==
==Solution NMR Structure of BCMA==
<StructureSection load='2kn1' size='340' side='right'caption='[[2kn1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2kn1' size='340' side='right'caption='[[2kn1]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kn1]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KN1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kn1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KN1 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CY1:ACETAMIDOMETHYLCYSTEINE'>CY1</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2kmz|2kmz]], [[2kn0|2kn0]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CY1:ACETAMIDOMETHYLCYSTEINE'>CY1</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kn1 OCA], [https://pdbe.org/2kn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kn1 RCSB], [https://www.ebi.ac.uk/pdbsum/2kn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kn1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kn1 OCA], [https://pdbe.org/2kn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kn1 RCSB], [https://www.ebi.ac.uk/pdbsum/2kn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kn1 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN]] Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.  
[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN]] Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.<ref>PMID:10903733</ref> <ref>PMID:10801128</ref> <ref>PMID:10973284</ref>
[https://www.uniprot.org/uniprot/TNR17_HUMAN TNR17_HUMAN] Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.<ref>PMID:10903733</ref> <ref>PMID:10801128</ref> <ref>PMID:10973284</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cuervo, H]]
[[Category: Cuervo H]]
[[Category: Day, E S]]
[[Category: Day ES]]
[[Category: Krushinskie, D]]
[[Category: Krushinskie D]]
[[Category: Pellegrini, M]]
[[Category: Pellegrini M]]
[[Category: Perroud, M]]
[[Category: Perroud M]]
[[Category: Schneider, P]]
[[Category: Schneider P]]
[[Category: Strauch, K]]
[[Category: Strauch K]]
[[Category: Sun, Y]]
[[Category: Sun Y]]
[[Category: Willen, L]]
[[Category: Willen L]]
[[Category: Zheng, T S]]
[[Category: Zheng TS]]
[[Category: April]]
[[Category: Baff]]
[[Category: Bcma]]
[[Category: Crd]]
[[Category: Signaling protein]]
[[Category: Tnf receptor]]
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