2l26: Difference between revisions
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==Rv0899 from Mycobacterium tuberculosis contains two separated domains== | ==Rv0899 from Mycobacterium tuberculosis contains two separated domains== | ||
<StructureSection load='2l26' size='340' side='right'caption='[[2l26 | <StructureSection load='2l26' size='340' side='right'caption='[[2l26]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2l26]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2l26]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L26 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l26 OCA], [https://pdbe.org/2l26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l26 RCSB], [https://www.ebi.ac.uk/pdbsum/2l26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l26 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l26 OCA], [https://pdbe.org/2l26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l26 RCSB], [https://www.ebi.ac.uk/pdbsum/2l26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l26 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/ARFA_MYCTU ARFA_MYCTU] Probably plays a role in ammonia secretion that neutralizes the medium at pH 5.5, although it does not play a direct role in ammonia transport. The OmpA-like domain (196-326) binds M.tuberculosis peptidoglycan. Overexpression in M.bovis or M.smegmatis gives channels with average conductance value of 1,600 +/- 100 pS, but this may not be physiologically relevant.<ref>PMID:12366842</ref> <ref>PMID:17573469</ref> <ref>PMID:21410778</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Gao | [[Category: Gao Y]] | ||
[[Category: Huang | [[Category: Huang H]] | ||
[[Category: Li | [[Category: Li J]] | ||
[[Category: Shi | [[Category: Shi C]] | ||
[[Category: Tian | [[Category: Tian C]] | ||
[[Category: Wu | [[Category: Wu K]] | ||
