5mrl: Difference between revisions

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<StructureSection load='5mrl' size='340' side='right'caption='[[5mrl]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
<StructureSection load='5mrl' size='340' side='right'caption='[[5mrl]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mrl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MRL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MRL FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mrl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MRL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F2M:(~{E})-~{N}-(FURAN-2-YLMETHYL)-~{N}-METHYL-PROP-1-EN-1-AMINE'>F2M</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAOB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F2M:(~{E})-~{N}-(FURAN-2-YLMETHYL)-~{N}-METHYL-PROP-1-EN-1-AMINE'>F2M</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monoamine_oxidase Monoamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mrl OCA], [https://pdbe.org/5mrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mrl RCSB], [https://www.ebi.ac.uk/pdbsum/5mrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mrl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mrl OCA], [http://pdbe.org/5mrl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mrl RCSB], [http://www.ebi.ac.uk/pdbsum/5mrl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mrl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN]] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.  
[https://www.uniprot.org/uniprot/AOFB_HUMAN AOFB_HUMAN] Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Monoamine oxidase]]
[[Category: Binda C]]
[[Category: Binda, C]]
[[Category: Corne R]]
[[Category: Corne, R]]
[[Category: De Deurwaerdere P]]
[[Category: Deurwaerdere, P De]]
[[Category: Fall Y]]
[[Category: Fall, Y]]
[[Category: Leone C]]
[[Category: Leone, C]]
[[Category: Marco-Contelles J]]
[[Category: Marco-Contelles, J]]
[[Category: Ramsay RR]]
[[Category: Ramsay, R R]]
[[Category: Valeri A]]
[[Category: Valeri, A]]
[[Category: Valoti M]]
[[Category: Valoti, M]]
[[Category: Enzyme]]
[[Category: Inhibitor]]
[[Category: Neurodegeneration]]
[[Category: Oxidoreductase]]