5mwo: Difference between revisions

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<StructureSection load='5mwo' size='340' side='right'caption='[[5mwo]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
<StructureSection load='5mwo' size='340' side='right'caption='[[5mwo]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mwo]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MWO OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MWO FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mwo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MWO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=J6W:(5-methyl-1-benzothiophen-2-yl)methanol'>J6W</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.962&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mwo OCA], [http://pdbe.org/5mwo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mwo RCSB], [http://www.ebi.ac.uk/pdbsum/5mwo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mwo ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=J6W:(5-methyl-1-benzothiophen-2-yl)methanol'>J6W</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mwo OCA], [https://pdbe.org/5mwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mwo RCSB], [https://www.ebi.ac.uk/pdbsum/5mwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mwo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU]] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5mwo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mwo" style="background-color:#fffaf0;"></div>
==See Also==
*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Abell, C]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Blundell, T L]]
[[Category: Abell C]]
[[Category: Chan, D S.H]]
[[Category: Blundell TL]]
[[Category: Coyne, A G]]
[[Category: Chan DS-H]]
[[Category: Matak-Vinkovic, D]]
[[Category: Coyne AG]]
[[Category: McConnell, B]]
[[Category: Matak-Vinkovic D]]
[[Category: Mendes, V]]
[[Category: McConnell B]]
[[Category: Thomas, S E]]
[[Category: Mendes V]]
[[Category: Ethr]]
[[Category: Thomas SE]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Repressor]]
[[Category: Tetr]]
[[Category: Transcription]]

Latest revision as of 17:52, 8 November 2023

Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.

5mwo, resolution 1.96Å

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