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<StructureSection load='5mxu' size='340' side='right'caption='[[5mxu]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='5mxu' size='340' side='right'caption='[[5mxu]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mxu]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MXU FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mxu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_simplicissimum Penicillium simplicissimum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MXU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Vanillyl-alcohol_oxidase Vanillyl-alcohol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.38 1.1.3.38] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxu OCA], [http://pdbe.org/5mxu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mxu RCSB], [http://www.ebi.ac.uk/pdbsum/5mxu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mxu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxu OCA], [https://pdbe.org/5mxu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mxu RCSB], [https://www.ebi.ac.uk/pdbsum/5mxu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VAOX_PENSI VAOX_PENSI]] Catalyzes the conversion of vanillin alcohol to vanillin, and also the conversion of a wide range of phenolic compounds bearing side chains of variable size at the para position of the aromatic ring. Crucial for the degradation of the secondary metabolites derived from the degradation of the lignin. Catalyzes besides the oxidation of 4-hydroxybenzyl alcohols, the oxidative deamination of 4-hydroxybenzylamines, the oxidative demethylation of 4-(methoxy-methyl)phenols and the oxidative hydration of 4-allylphenols. Most active with 4-allylphenols.  
[https://www.uniprot.org/uniprot/VAOX_PENSI VAOX_PENSI] Catalyzes the conversion of vanillin alcohol to vanillin, and also the conversion of a wide range of phenolic compounds bearing side chains of variable size at the para position of the aromatic ring. Crucial for the degradation of the secondary metabolites derived from the degradation of the lignin. Catalyzes besides the oxidation of 4-hydroxybenzyl alcohols, the oxidative deamination of 4-hydroxybenzylamines, the oxidative demethylation of 4-(methoxy-methyl)phenols and the oxidative hydration of 4-allylphenols. Most active with 4-allylphenols.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Vanillyl-alcohol oxidase]]
[[Category: Penicillium simplicissimum]]
[[Category: Allan, R C]]
[[Category: Allan RC]]
[[Category: Berkel, W J.H van]]
[[Category: Binda C]]
[[Category: Binda, C]]
[[Category: Ewing TA]]
[[Category: Ewing, T A]]
[[Category: Fraaije MW]]
[[Category: Fraaije, M W]]
[[Category: Gygli G]]
[[Category: Gygli, G]]
[[Category: Mattevi A]]
[[Category: Mattevi, A]]
[[Category: Nguyen Q-T]]
[[Category: Nguyen, Q T]]
[[Category: Romero E]]
[[Category: Romero, E]]
[[Category: Van Berkel WJH]]
[[Category: Oxidoreductase]]
[[Category: Vanillyl alcohol oxidase]]
[[Category: Y503f mutant]]
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