1ccf: Difference between revisions

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==How an Epidermal Growth Factor (EGF)-Like Domain Binds Calcium-High Resolution NMR Structure of the Calcium Form of the NH2-Terminal EGF-Like Domain in Coagulation Factor X==
==How an Epidermal Growth Factor (EGF)-Like Domain Binds Calcium-High Resolution NMR Structure of the Calcium Form of the NH2-Terminal EGF-Like Domain in Coagulation Factor X==
<StructureSection load='1ccf' size='340' side='right'caption='[[1ccf]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
<StructureSection load='1ccf' size='340' side='right'caption='[[1ccf]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ccf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CCF FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ccf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CCF FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BH2:(3R)-3-HYDROXY-L-ASPARTIC+ACID'>BH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ccf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ccf OCA], [https://pdbe.org/1ccf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ccf RCSB], [https://www.ebi.ac.uk/pdbsum/1ccf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ccf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ccf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ccf OCA], [https://pdbe.org/1ccf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ccf RCSB], [https://www.ebi.ac.uk/pdbsum/1ccf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ccf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FA10_BOVIN FA10_BOVIN]] Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.  
[https://www.uniprot.org/uniprot/FA10_BOVIN FA10_BOVIN] Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bovin]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Drakenberg, T]]
[[Category: Drakenberg T]]
[[Category: Persson, M]]
[[Category: Persson M]]
[[Category: Selander-Sunnerhagen, M]]
[[Category: Selander-Sunnerhagen M]]
[[Category: Stenflo, J]]
[[Category: Stenflo J]]
[[Category: Teleman, O]]
[[Category: Teleman O]]
[[Category: Ullner, M]]
[[Category: Ullner M]]
[[Category: Coagulation factor]]