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==NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor==
==NMR structure of hepatitis c virus ns3 serine protease complexed with the non-covalently bound phenethylamide inhibitor==
<StructureSection load='2k1q' size='340' side='right'caption='[[2k1q]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2k1q' size='340' side='right'caption='[[2k1q]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hepc 9hepc]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K1Q FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k1q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K1Q FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE3:4-(2-AMINOETHYL)-3-CHLOROBENZOIC+ACID'>FE3</scene>, <scene name='pdbligand=IBU:2-METHYLPROPYL+HYDROGEN+CARBONATE'>IBU</scene>, <scene name='pdbligand=OBF:(2S)-2-AMINO-4,4-DIFLUOROBUTANOIC+ACID'>OBF</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE3:4-(2-AMINOETHYL)-3-CHLOROBENZOIC+ACID'>FE3</scene>, <scene name='pdbligand=IBU:2-METHYLPROPYL+HYDROGEN+CARBONATE'>IBU</scene>, <scene name='pdbligand=OBF:(2S)-2-AMINO-4,4-DIFLUOROBUTANOIC+ACID'>OBF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bt7|1bt7]], [[1dwx|1dwx]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k1q OCA], [https://pdbe.org/2k1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k1q RCSB], [https://www.ebi.ac.uk/pdbsum/2k1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k1q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k1q OCA], [https://pdbe.org/2k1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k1q RCSB], [https://www.ebi.ac.uk/pdbsum/2k1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k1q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P90191_9HEPC P90191_9HEPC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hepacivirus C]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bazzo, R]]
[[Category: Bazzo R]]
[[Category: Cicero, D O]]
[[Category: Cicero DO]]
[[Category: Eliseo, T]]
[[Category: Eliseo T]]
[[Category: Gallo, M]]
[[Category: Gallo M]]
[[Category: Pennestri, M]]
[[Category: Pennestri M]]
[[Category: Envelope protein]]
[[Category: Helicase]]
[[Category: Hepatitis c virus]]
[[Category: Hydrolase]]
[[Category: Non covalent inhibitor]]
[[Category: Ns3]]
[[Category: Nucleotide-binding]]
[[Category: Rna replication]]
[[Category: Serine protease]]
[[Category: Transmembrane]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/2k1q"