7wmc: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7wmc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WMC FirstGlance]. <br>
<table><tr><td colspan='2'>[[7wmc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WMC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2IQ:2-(hexylamino)ethanoic+acid'>2IQ</scene>, <scene name='pdbligand=XA6:(2S)-3-(4-aminocarbonylphenyl)-2-azanyl-propanoic+acid'>XA6</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2IQ:2-(hexylamino)ethanoic+acid'>2IQ</scene>, <scene name='pdbligand=XA6:(2S)-3-(4-aminocarbonylphenyl)-2-azanyl-propanoic+acid'>XA6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wmc OCA], [https://pdbe.org/7wmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wmc RCSB], [https://www.ebi.ac.uk/pdbsum/7wmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wmc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wmc OCA], [https://pdbe.org/7wmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wmc RCSB], [https://www.ebi.ac.uk/pdbsum/7wmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wmc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/NNMT_HUMAN NNMT_HUMAN]] Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
[https://www.uniprot.org/uniprot/NNMT_HUMAN NNMT_HUMAN] Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==