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==Signal recognition particle-docking protein FtsY==
==Signal recognition particle-docking protein FtsY==
<StructureSection load='5niy' size='340' side='right' caption='[[5niy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='5niy' size='340' side='right'caption='[[5niy]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5niy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NIY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NIY FirstGlance]. <br>
<table><tr><td colspan='2'>[[5niy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NIY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BK350_09725, BK355_12030, BK400_00245 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5niy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5niy OCA], [http://pdbe.org/5niy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5niy RCSB], [http://www.ebi.ac.uk/pdbsum/5niy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5niy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5niy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5niy OCA], [https://pdbe.org/5niy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5niy RCSB], [https://www.ebi.ac.uk/pdbsum/5niy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5niy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A1M2U897_ECOLX A0A1M2U897_ECOLX]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.[HAMAP-Rule:MF_00920]
[https://www.uniprot.org/uniprot/FTSY_ECOLI FTSY_ECOLI] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.<ref>PMID:8194520</ref> <ref>PMID:9305630</ref> <ref>PMID:11735405</ref> <ref>PMID:11741850</ref> <ref>PMID:15148364</ref> <ref>PMID:17682051</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5niy" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5niy" style="background-color:#fffaf0;"></div>
==See Also==
*[[Signal recognition particle receptor|Signal recognition particle receptor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Kempf, G]]
[[Category: Large Structures]]
[[Category: Lapouge, K]]
[[Category: Kempf G]]
[[Category: Sinning, I]]
[[Category: Lapouge K]]
[[Category: Stjepanovic, G]]
[[Category: Sinning I]]
[[Category: Gtpase]]
[[Category: Stjepanovic G]]
[[Category: Nucleotide]]
[[Category: Receptor]]
[[Category: Signaling protein]]
[[Category: Srp]]
Retrieved from "https://proteopedia.org/5niy"