8hib: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 8hib is ~~ON HOLD until Paper Publication~~

==The crystal structure of Pygo2-LDB1-SSBP2 triple complex==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[8hib]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HIB FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hib OCA], [https://pdbe.org/8hib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hib RCSB], [https://www.ebi.ac.uk/pdbsum/8hib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hib ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/LDB1_HUMAN LDB1_HUMAN] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Play a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Wang HY]]

[[Category: Xu WQ]]

[[Category: Yan XX]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8hib is ON HOLD  until Paper Publication
+==The crystal structure of Pygo2-LDB1-SSBP2 triple complex==
+<StructureSection load='8hib' size='340' side='right'caption='[[8hib]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8hib]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HIB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HIB FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hib FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hib OCA], [https://pdbe.org/8hib PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hib RCSB], [https://www.ebi.ac.uk/pdbsum/8hib PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hib ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LDB1_HUMAN LDB1_HUMAN] Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Play a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Wang HY]]
+[[Category: Xu WQ]]
+[[Category: Yan XX]]