5xtx: Difference between revisions
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==Crystal Structure of Transketolase in complex with TPP intermediate VII from Pichia Stipitis== | ==Crystal Structure of Transketolase in complex with TPP intermediate VII from Pichia Stipitis== | ||
<StructureSection load='5xtx' size='340' side='right' caption='[[5xtx]], [[Resolution|resolution]] 1.05Å' scene=''> | <StructureSection load='5xtx' size='340' side='right'caption='[[5xtx]], [[Resolution|resolution]] 1.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5xtx]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5xtx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Scheffersomyces_stipitis_CBS_6054 Scheffersomyces stipitis CBS 6054]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XTX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XTX FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8ML:2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-2-[(2S,3S,4R,5R)-1,2,3,4,5-pentakis(oxidanyl)-6-phosphonooxy-hexan-2-yl]-1,3-thiazolidin-5-yl]ethyl+phosphono+hydrogen+phosphate'>8ML</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.049Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8ML:2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methylidene-2-[(2S,3S,4R,5R)-1,2,3,4,5-pentakis(oxidanyl)-6-phosphonooxy-hexan-2-yl]-1,3-thiazolidin-5-yl]ethyl+phosphono+hydrogen+phosphate'>8ML</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xtx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xtx OCA], [https://pdbe.org/5xtx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xtx RCSB], [https://www.ebi.ac.uk/pdbsum/5xtx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xtx ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TKT_PICST TKT_PICST] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 22: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Transketolase|Transketolase]] | *[[Transketolase 3D structures|Transketolase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Scheffersomyces stipitis CBS 6054]] | ||
[[Category: Hsu | [[Category: Hsu NS]] | ||
[[Category: Li | [[Category: Li TL]] | ||
[[Category: Wang | [[Category: Wang YL]] | ||
Latest revision as of 08:13, 22 November 2023
Crystal Structure of Transketolase in complex with TPP intermediate VII from Pichia Stipitis
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