5xwv: Difference between revisions

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==Substrate-bound Structure of a Ketoreductase from the Second Module of the amphotericin Polyketide Synthases==
==Substrate-bound Structure of a Ketoreductase from the Second Module of the amphotericin Polyketide Synthases==
<StructureSection load='5xwv' size='340' side='right' caption='[[5xwv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5xwv' size='340' side='right'caption='[[5xwv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xwv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_4.1459 As 4.1459]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XWV FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xwv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_nodosus Streptomyces nodosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XWV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8H6:S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl]+(2R)-2-methyl-3-oxidanylidene-pentanethioate'>8H6</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">amphB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=40318 AS 4.1459])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8H6:S-[2-[3-[[(2R)-3,3-dimethyl-2,4-bis(oxidanyl)butanoyl]amino]propanoylamino]ethyl]+(2R)-2-methyl-3-oxidanylidene-pentanethioate'>8H6</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwv OCA], [http://pdbe.org/5xwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xwv RCSB], [http://www.ebi.ac.uk/pdbsum/5xwv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwv OCA], [https://pdbe.org/5xwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xwv RCSB], [https://www.ebi.ac.uk/pdbsum/5xwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q93NW7_9ACTN Q93NW7_9ACTN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: As 4 1459]]
[[Category: Large Structures]]
[[Category: Liu, C]]
[[Category: Streptomyces nodosus]]
[[Category: Zheng, J]]
[[Category: Liu C]]
[[Category: Ketoreductase]]
[[Category: Zheng J]]
[[Category: Modular polyketide synthease]]
[[Category: Oxidoreductase]]