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==Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site==
==Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site==
<StructureSection load='5y53' size='340' side='right' caption='[[5y53]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='5y53' size='340' side='right'caption='[[5y53]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5y53]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y53 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y53 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5y53]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y53 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AL2, At3g11200, F11B9.12, F9F8.2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.598&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RING-type_E3_ubiquitin_transferase RING-type E3 ubiquitin transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.27 2.3.2.27] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y53 OCA], [https://pdbe.org/5y53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y53 RCSB], [https://www.ebi.ac.uk/pdbsum/5y53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y53 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y53 OCA], [http://pdbe.org/5y53 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y53 RCSB], [http://www.ebi.ac.uk/pdbsum/5y53 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y53 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ALFL2_ARATH ALFL2_ARATH]] Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. [[http://www.uniprot.org/uniprot/DRIP1_ARATH DRIP1_ARATH]] E3 ubiquitin-protein ligase that acts as a negative regulator of the response to water stress. Mediates ubiquitination and subsequent proteasomal degradation of the drought-induced transcriptional activator DREB2A. Functionally redundant with DRIP2.<ref>PMID:18552202</ref> 
[https://www.uniprot.org/uniprot/ALFL2_ARATH ALFL2_ARATH] Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: RING-type E3 ubiquitin transferase]]
[[Category: Large Structures]]
[[Category: Huang, Y]]
[[Category: Huang Y]]
[[Category: Peng, L]]
[[Category: Peng L]]
[[Category: Wang, L L]]
[[Category: Wang LL]]
[[Category: Alfin-like family protein]]
[[Category: Complex]]
[[Category: Gene regulation]]
[[Category: Prc1 interactor]]
Retrieved from "https://proteopedia.org/5y53"