5y97: Difference between revisions

<table><tr><td colspan='2'>[[5y97]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichosanthes_anguina Trichosanthes anguina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5Y97 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900004:beta-lactose'>PRD_900004</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5y97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y97 OCA], [https://pdbe.org/5y97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5y97 RCSB], [https://www.ebi.ac.uk/pdbsum/5y97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5y97 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SGSL_TRIAN SGSL_TRIAN] Seed lectin similar to type 2 ribosome-inactivating proteins (PubMed:23897472, PubMed:11375527). The Aalpha and Abeta chains constitute the rRNA glycosidase domain and the B chain the carbohydrate-binding lectin domain (PubMed:23897472). Is predicted to have no glycosidase activity and, hence, to be non-toxic, due to small changes in both the nucleotide binding and carbohydrate binding capabilities (PubMed:23897472, PubMed:11375527). Binds galactose and derivatives with a preference for the beta-anomeric forms (PubMed:8799450, PubMed:10877067). Binds prophyrins (PubMed:10877067). Has hemagglutinating activity towards rabbit and human erythrocytes (PubMed:8799450, PubMed:10877067).<ref>PMID:10877067</ref> <ref>PMID:11375527</ref> <ref>PMID:23897472</ref> <ref>PMID:8799450</ref>  

[[Category: Chandran T]]

[[Category: Sivaji N]]

[[Category: Surolia A]]

[[Category: Vijayan M]]