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==Crystal Structure of Hypothetical protein (Rv3272) from Mycobacterium tuberculosis==
==Crystal Structure of Hypothetical protein (Rv3272) from Mycobacterium tuberculosis==
<StructureSection load='5yit' size='340' side='right' caption='[[5yit]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
<StructureSection load='5yit' size='340' side='right'caption='[[5yit]], [[Resolution|resolution]] 2.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5yit]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YIT FirstGlance]. <br>
<table><tr><td colspan='2'>[[5yit]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YIT FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv3272 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.79&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yit OCA], [http://pdbe.org/5yit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yit RCSB], [http://www.ebi.ac.uk/pdbsum/5yit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yit ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yit OCA], [https://pdbe.org/5yit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yit RCSB], [https://www.ebi.ac.uk/pdbsum/5yit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yit ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COATR_MYCTU COATR_MYCTU] Probably involved in fatty acid metabolism. Binds to fatty acyl-CoAs of varying carbon chain lengths, with the highest binding affinity for palmitoyl-CoA (C16:0). In vitro, alters the cell wall lipid profile and protects mycobacteria from acidic, oxidative and antibiotic stress. May play a significant role in host-pathogen interaction.<ref>PMID:30342240</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Myctu]]
[[Category: Large Structures]]
[[Category: Karade, S S]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Pratap, J V]]
[[Category: Karade SS]]
[[Category: Coa transferase family iii]]
[[Category: Pratap JV]]
[[Category: Interlocked dimer]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Rv3272]]
[[Category: Transferase]]
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